Research Lead / Senior Epidemiologist

We are currently seeking candidates to fill a Research Lead / Senior Epidemiologist role.

You will have the scope and capability to develop research ideas, coordinate, conduct and communicate high quality, scientific research for both commercial and academic purposes. The successful candidate will work within a small, experienced team of international researchers and alongside our clinical, statistical and database colleagues. This is a fantastic opportunity to gain experience within an internationally recognised research organisation involved in the analysis and dissemination of real-life research from large-scale observational studies and pragmatic randomised controlled trials.

This role can be based in our UK (Cambridge or Norfolk), Singapore or Brisbane offices on a full or part time basis. For highly experienced individuals international remote working will be considered.

Primary responsibilities

  • Lead research proposals for academic and commercial clients.
  • Develop statistical analysis plans and conduct analyses for clinical database studies and pragmatic randomised controlled trials.
  • Liaise with study sponsors and steering committee experts throughout the project.
  • Take leadership of a project team from idea generation to delivery of the study outputs.
  • Critically review the work of other members of the research team and mentor less experienced members as necessary.
  • Contribute, as an author, to journal publications, conference abstracts and posters.
  • Present at international conferences.


  • Postgraduate degree in life sciences (e.g. MSc, PhD), epidemiology, biostatistics or equivalent with 3-5 years of experience

Experience and Key Skills

  • Demonstrable experience of large clinical database research ideally with practical experience of using Clinical Practice Research Datalink (CPRD) data or equivalent
  • Experience of leading health research projects from start to completion
  • Analysis and dissemination of real-life research from large-scale observational studies
  • Protocol writing
  • Manuscript writing
  • Authorship of journal publications (at least 10 peer-reviewed publications)
  • Working with large databases (in excess of 100k)
  • Statistical analysis using Stata, R, SQL or MySQL
  • Biostatistical experience: regressions (logistics, conditional), survival analysis
  • Client relations, liaising with external parties internationally, strong leadership and presentation skills
  • Excellent written and verbal English communication skills

About The Observational Pragmatic Research Institute (OPRI)

OPRI is an independent organisation with a focus on generating real world clinical evidence with a primary focus on respiratory care. OPRI aims to improve disease management and patient outcomes by undertaking the highest quality observational and pragmatic clinical research. OPRI focuses on identifying real-life factors that influence outcomes and real-life effectiveness both in terms of disease management and pharmacological interventions. By collaborating with world-renowned clinical, academic and industry partners, OPRI drives a vision for inclusion of real-life research into all aspects of medical research and clinical practice. OPRI has published over 100 papers and is considered a dynamic and progressive company leading in real life respiratory research globally.

Contract and Salary

Starting salary is dependent on qualifications and experience.
Immediate start is available.

Contact Us

Please send your CV with a covering letter summarising your suitability for the role. Candidates will be required to undertake a remote skills test prior to the interview.

We look forward to hearing from you.